Are you want to make responsive website? There are many frameworks kits for creating responsive websites. If you search of a lightweight and focused resource for responsive layouts, here is Responsive Boilerplate.
It is lightweight (3kb) micro-framework, elegant and minimalistic CSS3 grid system, made with only one container and 12 columns.
The boilerplate has a single container + a 12-column grid and supports any content with images, video or fluid media with major breakpoints.
It`s very easy to use and understand, pre-packed with some extra css helpers for mobile devices.
Adapt to any screen size, including fluid media; images and video and pre-configured with 4 breakpoints, just to make your job easier.
Sublime text Snippets.
Include in the package: PSD Template, HTML5 starting point file for fast development and two Sublime Text snippets for CSS grid and HTML file.
Mobile AeonNav Optimized.